Queen regnant of Spain (born 1830) from 1836 to her death in 1904. Manuscript DS, in Spanish, signed "Isabel," one page, 8.5 x 11.25, 1856. Document announcing a birth to King Ferdinand II of Naples and Sicily. Neatly signed at the conclusion by the Queen. In fine condition, with central horizontal and vertical folds, and some scattered light toning. Accompanied by the original transmittal leaf with the red wax seal intact. RRAuction COA.