Co-founder, with his brother William, of the Mayo Clinic. TLS signed “C. H. Mayo,” one page, 8 x 10.5, personal letterhead, March 2, 1931. A letter to Roger Metcalf, who had expressed interest in becoming a doctor. In part: “There is always room in medicine for those who are willing to work. It costs a good deal to go through the medical schools of the present day one can save a year’s time on the whole course…. The medical course takes in all branches of medicine and one does not specialize until after graduation. During your years of work after you have finished, or perhaps by the time you have finished your hospital internship, you may find you have a special liking for some particular branch of the work and then you can specialize in that.” In fine condition, with intersecting mailing folds, one along first initial. R&R COA.