Co- founder, with his brother Charles, of the renowned Mayo Clinic. TLS signed “W. J. Mayo,” one page, 7.75 x 10.5, personal letterhead, October 11, 1934. A letter to Roger Metcalf, who had expressed interest in becoming a doctor. In part: “As a general thing, I think three years premedical work is sufficient…. If one is taking up clinical medicine, it is important to choose a medical school that lays stress on clinical training, and of these, Harvard and the University of Pennsylvania are excellent.” In fine condition, with bisecting mailing folds. R&R COA.