English physician and scientist (1749-1823) often called the ‘father of immunology,’ who successfully tested his smallpox inoculation in 1796. Partial ALS, one page, 4.5 x 3.75, [July 30, 1812 annotated on the reverse in another hand]. The conclusion of a letter to "Mr. Drayton, St. George's Square, Cheltenham," in full: "should be able to manage it with a tightened string. With best wishes to you & yours, I remain yrs truly, Edw'd Jenner." Addressed on the reverse in Jenner's hand. In very good condition, with areas of repaired paper loss, and a block of toning from prior display.
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