King of Spain (born 1527) from 1556 until his death in 1598; his eventful reign included Spain’s conquest of the Philippines, the establishment of a colony in Florida, and the historic defeat of the Spanish Armada by the British in 1588. LS in Spanish, signed “Yo el Rey,” one page, 8.5 x 11.5, March 28, 1566. Untranslated letter to Pedro Afan, who served variously as Viceroy of Naples, Viceroy of Cataluna, and 1st Duke of Alcala de los Gazules, concerning the Marques of Pescara and the Princess of Francavila. In very good condition, with intersecting folds, scattered creases, an area of circular toning, and some show-through from docketing to reverse. RR Auction COA.