Canadian physician and researcher (1891–1941) who shared the 1923 Nobel Prize in Medicine for his role in the discovery of insulin. Rare ALS signed “Fred,” two pages, 7.75 x 10, October 19, 1930. Letter to “Beulah,” while painting in the wilderness with A. Y. Jackson. In part: “We are sitting in front of a nice warm fire…Outside it is cold, blowing, and blizzard with sleet and snow…The first three days were magnificent but the last three days have been rather bad. Pardon so much concerning weather but it is one of the essentials of painting, and in a place like this where there is everything to paint—rocks, trees, clouds, water—bad weather is a punishment. But it is great to be alive. I wonder why we live in a city.” In fine condition, with intersecting folds and a mild shade of overall toning. RRAuction COA.