American academic trauma surgeon (1805–1884). He is the subject of Thomas Eakins’ painting, The Gross Clinic, one of the most significant American paintings of the 19th century. ALS signed “S. D. Gross,” three pages on two adjoining sheets, 4.5 x 6.5, personal letterhead, November 21, 1881. Letter to Professor Benjamin Silliman. In part: “I have just received your kind and thoughtful letter & Miss Eleanor’s equally kind and thoughtful one reached me…I am glad to have it in my power to say that I am not any worse; decidedly better I am sure I am not. I am weak & feverish…I lectured at my usual hour this morning…I shall have three rest days this week.” In very good condition, with partially separated hinge, heavy horizontal folds, and scattered toning. RRAuction COA.