Commander-in-chief of the British army during the Revolutionary War (1717-1797) whose reputation was damaged due to allegations that he conducted an early form of germ warfare against Native Americans, a group he held in extremely low regard, using the deadly smallpox virus. ALS signed “JA,” one page, 7.5 x 9, December 11, 1742. Amherst writes from Ghent, in the midst of the War of the Austrian Succession, to his brother, Jack. In part: “I don’t know what I have done to you all but nobody writes me[.] Five or six packets come in at a time & I have no letters…. We have a cornet just coming over & if you will be so good to get my Irish Gunn put in good order & send it by him I shall be very much obliged to you, for I shall not only have occasion for it in a sporting way but in a military one. Cornet Holmes will bring it for me if you will put it secure in a wooden case & have it for him at Capt. Greenway’s next door….” In good condition, with intersecting folds, a few chips and tears (tape-repaired from reverse), toning, and scattered spotting. R&R COA.