Italian-born British nurse (1820–1910), popularly known as the “Lady with a Lamp,” who first came to prominence for her care of troops during the Crimean War. She pioneered modern nursing and hospital practice, and her prowess as a mathematician led her to develop a number of important innovations in the field of statistics. Pencil signature, “Ever yours affly, F. Nightingale,” on an off-white slip. Double gilt-matted and framed with a glossy portrait of Nightingale, to an overall size of 15.25 x 21.5. In fine condition, with a bisecting vertical fold. R&R COA.