Queen consort (1488-1536) of Aragon as the second wife of Ferdinand II of Aragon. Very rare manuscript DS in Spanish, signed "La Reyna [The Queen],"one page, 8.5 x 12, September 22, 1519. Untranslated document issued at Barcelona by Germaine of Foix as queen consort. Countersigned by her secretary, "Romeu." In very good to fine condition, with scattered light foxing and staining, and a small hole at the center.