Pioneering French microbiologist and chemist (1822–1895) who demonstrated the germ theory of disease and developed the first vaccine against rabies. Exceptional original 4.25 x 6.5 cabinet portrait by Pierre Petit of Paris (so noted along bottom border and on the reverse), signed in the lower border in ink, “L. Pasteur.” In fine condition, with subtle toning and soiling, and a bit of light foxing and surface marks. Quite uncommon in signed photographs of this quality! JSA/John Reznikoff Auction LOA and RRAuction COA.